The Danger Of Mixing Benadryl and Alcohol

Benadryl Generic name diphenhydramine; is an antihistamine that is used to deal with symptoms of allergy, and common cold (hay fever).

These symptoms include skin rash, runny nose, itching, itchy (eyes, nose, throat),  watery eyes, cough, and sneezing. They are a popular brand name for a lot of people who might have encountered any of these conditions.

Benadryl is an antihistamine that decreases the effects of the natural chemical histamine in our body. Histamine is involved in how our body’s immune response to allergens. This is the reason why a person gets reactions like itchy skin, stuffy nose, etc. when they come in contact with something they are allergic to. Do not use Benadryl if you are allergic to diphenhydramine.

benadryl and alcohol

Side Effects of Benadryl

  • Drowsiness
  • Headache
  • dizziness
  • constipation
  • blurred vision
  • stomach upset
  • dry mouth, nose, or throat

Can I Mix Benadryl With Alcohol?

Alcohol affects your liver more than Benadryl does. Both Benadryl and alcohol work on your central nervous system. Your CNS is made up of the brain and spinal cord. The problem here is that Benadryl and alcohol are both Central nervous system depressants.

These drugs can slow down your central nervous system. In fact, taking Benadryl and alcohol together is dangerous, as they tend to slow down your central nervous system too much. And this can lead to drowsiness, blurred vision and trouble carrying out mental and physical tasks which requires mental alertness.

In essence, both of them shouldn’t be used together. In certain cases, it is hazardous to use them together; like using them together while driving.

NB: Benadryl is meant for short-term use. It is advised you wait a while until you are done using it before you take any alcohol.

Some risks of mixing Benadryl and alcohol

1. Drowsiness
2. Loss of consciousness
3. Complications in older adults
4. Dehydration
5. Memory impairment
5. Dementia
6. Blurred vision

Also Read: Why Breast Thermography Is the Best Test


Benadryl is approved for the treatment of allergy symptoms only. It is not to be used for any other purpose. Just because Benadryl causes drowsiness, a lot of people may think it’s a great idea to use it as a sleeping aid. And some people may also think alcohol can be used as a sleep aid because it can make you sleepy. Only Benadryl generic form diphenhydramine is approved as a sleep aid.

We advise that, if you want a good night sleep, please don’t even make the mistake of taking a glass of wine (alcohol) and a dose of Benadryl will help you. The misuse of Benadryl and alcohol may make you dizzy and then prevent you from having a good sleep all through the night.

benadryl and alcohol

It is recommended to only use Benadryl to treat your allergy symptoms as it may interact negatively with other medications or sleep aids.

Driving warning

Benadryl may cause a blur vision to an individual and may also impair their thinking or reactions. So, do not use Benadryl or take with alcohol if you drive. Be careful if you drive, use machinery, or do anything that requires you to see clearly or stay alert.

As you already know that drinking alcohol while driving is not safe, then mixing with Benadryl is more dangerous.

For Aged people?

For people of all ages, using these drugs together makes it harder to control body motions properly, and in aged people, it may be even riskier.

Taking Benadryl with alcohol can cause particular problems for aged people. For example, it may increase their risk of falls and may lead to stroke. So, do not give seniors this mixture.

What are Hidden sources of alcohol?

Since you now know that mixing these 2 drugs is not safe, you need to be aware of sources of hidden alcohol. You need to avoid them while taking benadryl.

Some medications have 10% of alcohol in them. These drugs may interact with Benadryl. These include drugs like cough syrup and laxatives.

To avoid misuse and risk of an accident please ensure you read the labels on all drugs you are taking, or you want to purchase.

What other drugs will affect Benadryl?

If you are taking over-the-counter medicines, vitamins, and herbal products, or any prescription drugs, please talk to your doctor to know if it’s safe to use with Benadryl. Some medicines can cause unwanted effects when used together.

Taking Benadryl with other drugs can slow your breathing or make you sleepy. Consult your doctor before taking Benadryl with narcotic pain medicine, sleeping pill, medicine for anxiety, seizures, or depression.

benadryl and alcohol

When Can You Call Your Doctor & Stop using these drugs?

If mistakenly you took Benadryl and Alcohol together or Benadryl alone and you experience any of these; call your doctor immediately and stop using if you have:

  • A pounding heartbeats
  • A painful or difficult urination
  • A fluttering in your chest
  • A little or no urinating
  • A tightness in your jaw or neck
  • You feel like you might pass out

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